Current time in Korea 07:43 Dec 08 (Sun) Year 2019 KCS KCS Publications
KCS Publications
My Journal Log In Register
HOME > Search > Browsing(BKCS) > Archives

Bulletin of the Korean Chemical Society (BKCS)

ISSN 0253-2964(Print)
ISSN 1229-5949(Online)
Volume 24, Number 4
BKCSDE 24(4)
April 20, 2003 

Convenient Synthesis of Optically Pure a-Mono and a, a-Disubstituted b-Amino Acids
Hyun Soo Lee, Jung Dae Park, Dong H. Kim
a-Monosubstituted b-amino acids, a, a-Disubstituted b-amino acids, b-Lactams, (S)-Phenylethylamine
Optically pure a-mono- and a, a-disubstituted b-amino acids were conveniently prepared in four steps and in 27-40% overall yields from the correspondingly substituted racemic b-hydroxy acids that can be readily obtained from diethyl malonate. In the synthesis, (S)-phenylethylamine has been used as a resolving agent and as a source of the amino group in the b-amino acids.
467 - 472
Full Text