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Bulletin of the Korean Chemical Society (BKCS)

ISSN 0253-2964(Print)
ISSN 1229-5949(Online)
Volume 23, Number 7
BKCSDE 23(7)
July 20, 2002 
 
Title
 One-Pot Synthesis of 2H-Pyrans by Indium(III) Chloride-Catalyzed Reactions.Efficient Synthesis of Pyranocoumarins, Pyranophenalenones, and Pyranoquinolinones
Author
 Yong Rok Lee, Do Hoon Kim, Jae-Jin Shim, Seog K. Kim, Jung Hag Park, Jin Soon Cha, Chong-Soon Lee
Keywords
 Caspase 3, Nonpeptidic inhibitor, Apoptosis, Isoquinoline derivatives.
Abstract
 An efficient synthesis of 2H-pyrans is achieved by indium (Ⅲ) chloride-catalyzed reactions of 1,3-dicarbonyl compounds with a variety of α,β-unsaturated aldehydes in moderate yields. This method has been applied to the synthesis of pyranocoumarins, pyranophenalenones, and pyranoquinolinone alkaloids.
Page
 998 - 1002
Full Text
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